Relay Therapeutics 401(k) Plan

Relay Therapeutics 401(k) Plan is a defined-contribution plan covering 261 active participants and 142 other participants entitled to future benefits, with total plan assets of $43.7 million as of December 31, 2024. The plan is administered by Relay Therapeutics, Inc. and uses Vanguard as recordkeeper with Cambridge Investment Research as broker-dealer and advisor. The plan features safe harbor matching contributions and automatic enrollment at 6% with immediate vesting.

Participants: 406 Plan assets: $43,657,830 Plan number: 001 Form 5500 plan year: 2024 Last verified: Jun 16, 2026 View Form 5500
Match
100% + 50% Match
Vesting
Participants are immediately vested in all contributions and actual earnings or losses thereon.
Investment Options
42 funds
Auto-Enrollment
Participants are automatically enrolled into the Plan at 6% of eligible compensation with the ability to elect not to participate or change their deferral election.
Plan Size
$43,657,830

By Zac Murphy, CFA charterholder and CFP professional. Published June 16, 2026. Verified against Form 5500 plan year 2024.

Get a personalized look at your Relay Therapeutics 401(k) options

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Fund lineup

Fund Asset Class Type
Vanguard Target Retirement 2050 Fund Target-date Index
Vanguard Target Retirement 2055 Fund Target-date Index
Vanguard Target Retirement 2045 Fund Target-date Index
Vanguard 500 Index Adm US Large Cap Index
Vanguard Target Retirement 2040 Fund Target-date Index
Vanguard Total Stock Market Index Adm US Large Cap Index
Vanguard Target Retirement 2060 Fund Target-date Index
Vanguard Target Retirement 2030 Fund Target-date Index
Vanguard Target Retirement 2035 Fund Target-date Index
Vanguard Federal Money Market Inv Money Market Active
JPMorgan Growth Advantage R6 US Large Cap Active
Vanguard Total Intl Stock Index Adm International Equity Index
Vanguard Target Retirement 2025 Fund Target-date Index
Vanguard Mid Cap Index Adm US Mid Cap Index
Vanguard Target Retirement 2065 Fund Target-date Index
Vanguard Small Cap Index Adm US Small Cap Index
Fidelity Advisor Equity Growth US Large Cap Active
JPMorgan Mid Cap Growth R6 US Mid Cap Active
VANGUARD EQUITY INCOME ADM US Large Cap Active
Vanguard FTSE Social Index ADM US Large Cap Index
Calvert U.S. Large Cap Core Responsible Index I US Large Cap Index
DFA Intl Core Equity Portfolio Instl International Equity Active
BlackRock Total Return K Balanced/Allocation Active
Vanguard Windsor II Adm US Large Cap Active
Janus Henderson Venture N US Large Cap Active
BlackRock International K International Equity Active
Impax Global Environmental Markets Instl International Equity Active
Vanguard Real Estate Index Adm Real Estate Index
Putnam Emerging Markets Equity Fund R6 Emerging Markets Active
PIMCO Income Instl US Bonds Active
Federated Hermes Instl High Yield Bond R6 High Yield Bonds Active
Allspring Special Small Cap Value R6 US Small Cap Active
MFS Mid Cap Value R6 US Mid Cap Active
Vanguard Short-Term Invest Grade Adm US Bonds Active
Vanguard GNMA Adm US Bonds Active
Nuveen Core Impact Bond R6 US Bonds Active
PIMCO Real Return Instl TIPS Active
MFS Global Equity R6 International Equity Active
PGIM Global Total Return R6 International Bonds Active
Vanguard Target Retirement 2070 Fund Target-date Index
Vanguard Target Retirement Income Fund Target-date Index
Vanguard Target Retirement 2020 Fund Target-date Index

Why our allocations use only index funds

The actively managed funds in this plan cost more per year than the plan's index funds, which run roughly 0.02% to 0.06%. Decades of research on long-term active fund performance do not support reliable outperformance net of fees, which is why the allocation ideas below may consider using only the low-cost index options.

Employer match

Match summary
100% match on the first 2% of eligible compensation and 50% match on the next 4% of eligible compensation
Match cap 100% of pay
Effective match rate 6%
Vesting Participants are immediately vested in all contributions and actual earnings or losses thereon.
Waiting period Employees become eligible to participate immediately upon being hired by the Plan Sponsor.
$
Contribute this much to capture the full match
100% of your eligible pay, every paycheck.

100% match on the first 2% of eligible compensation and 50% match on the next 4% of eligible compensation Contributing less than 100% of your eligible pay leaves part of Relay Therapeutics's match unclaimed.

What the match is worth at your pay After 1 year of service, contributing 100%
Annual pay Your contribution Employer match Total to 401(k)

Estimates assume a constant salary and the match formula shown above. Your actual match depends on your plan's exact terms.

The cost of contributing only --%

On a $60,000 salary, contributing just half the match threshold would leave about -- in employer match unclaimed each year. Invested over 20 years at a hypothetical 7% annual return, that forgone match could have grown to roughly -- (a hypothetical illustration, not a projection). The match is the highest-return contribution you will make all year.

Sources

  • Plan metadata (employer, participants, assets, plan year): Form 5500 annual return/report, plan year 2024 -- view filing
  • Summary Plan Description (SPD) and fee disclosure (404a-5), where available from the plan administrator.

This page is for educational purposes only and does not constitute investment, tax, or legal advice, nor a recommendation to buy or sell any security. Information is drawn from public Form 5500 filings and plan documents and may be incomplete or out of date. You may consider consulting a qualified professional and confirming all details with your plan administrator before making decisions. Waterfall Planning is not affiliated with Relay Therapeutics.

Find your risk profile

Answer 13 questions to see which allocation fits your situation.

Question 1 of 13

Risk assessment methodology based on Grable, J. E., & Lytton, R. H. (1999). Financial risk tolerance revisited: The development of a risk assessment instrument. Financial Services Review, 8, 163-181.

Allocation ideas

Five sample mixes built from this plan's funds, from conservative to growth. Take the assessment above to see which one fits your risk profile.

Recommended for you (based on your risk profile)
Conservative
Conservative

Capital preservation with minimal market exposure, built from bonds and stable value.

US equity   International   Bonds   Stable value
PIMCO Income Instl 70%
Vanguard Federal Money Market Inv 30%
0% stocks / 100% bonds
Recommended for you (based on your risk profile)
Income & A Little Growth
Income & A Little Growth

Mostly bonds with a small stock sleeve for modest growth.

US equity   International   Bonds   Stable value
PIMCO Income Instl 49%
Vanguard Federal Money Market Inv 21%
Vanguard 500 Index Adm 19%
Vanguard Total Intl Stock Index Adm 8%
Vanguard Mid Cap Index Adm 3%
30% stocks / 70% bonds
Recommended for you (based on your risk profile)
Balanced
Balanced

A classic 60/40 split of stocks and bonds.

US equity   International   Bonds   Stable value
Vanguard 500 Index Adm 39%
PIMCO Income Instl 28%
Vanguard Total Intl Stock Index Adm 15%
Vanguard Federal Money Market Inv 12%
Vanguard Mid Cap Index Adm 6%
60% stocks / 40% bonds
Recommended for you (based on your risk profile)
Growth & Income
Growth & Income

Stock-heavy with a bond cushion for a long horizon.

US equity   International   Bonds   Stable value
Vanguard 500 Index Adm 52%
Vanguard Total Intl Stock Index Adm 20%
PIMCO Income Instl 14%
Vanguard Mid Cap Index Adm 8%
Vanguard Federal Money Market Inv 6%
80% stocks / 20% bonds
Recommended for you (based on your risk profile)
Growth
Growth

All stocks for maximum long-term growth potential, with higher short-term volatility.

US equity   International   Bonds   Stable value
Vanguard 500 Index Adm 65%
Vanguard Total Intl Stock Index Adm 25%
Vanguard Mid Cap Index Adm 10%
100% stocks / 0% bonds
Stay on track

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These allocation ideas are educational illustrations built from this plan's available funds and a standard risk-tolerance assessment. They are not personalized investment advice or a recommendation, and risk tolerance is only one factor in an investment decision. You may consider consulting a qualified professional before making changes to your account.